Why the study?
Does Type 1 diabetes with or without microangiopathy alter resting-state neural connectivity and cognitive functions compared to healthy controls?
Population
149 subjects: Type 1 diabetes mellitus patients with microangiopathy, T1DM patients without microangiopathy…
Comparison
Type 1 diabetes mellitus with or without… vs Healthy control subjects
Design
Cross-sectional
Authors
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Differential connectivity patterns in T1DM may signal microangiopathy-linked cognitive vulnerability; leaves open causality and requires longitudinal confirmation.
Does Type 1 diabetes with or without microangiopathy alter resting-state neural connectivity and cognitive functions compared to healthy controls?
Type 1 diabetes is associated with functional reorganization of neural networks that varies depending on the presence of microangiopathy, which correlates with cognitive performance.
Duinkerken et al. (2012) studied this question.
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