What question did this study set out to answer?

To evaluate the insecticide resistance status and mechanisms in Anopheles mosquitoes in Nigeria over a five-year period.

August 12, 2026Malaria JournalOpen Access

Insecticide resistance profile of the Anopheles gambiae s.l. mosquitoes in Nigeria: a 5-year malaria vector surveillance report

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Randomized trial assessed insecticide resistance in Anopheles mosquitoes, indicating significant challenges for malaria control in Nigeria.

To evaluate the insecticide resistance status and mechanisms in Anopheles mosquitoes in Nigeria over a five-year period.
Collected immature mosquitoes from 72 local government areas between 2020 and 2024.
Tested resistance to permethrin, deltamethrin, alphacypermethrin, and pirimiphos-methyl according to WHO criteria.
Utilized molecular tests to determine kdr-L995F mutation and assessed metabolic enzyme involvement.
95% of mosquitoes tested belonged to the Anopheles gambiae complex, with Anopheles coluzzii making up 79.8%.
Mortality to permethrin remained low (0-75%), with widespread pyrethroid resistance observed.
Significant spatial and temporal trends in insecticide susceptibility were noted, alongside resistance mechanisms involving oxidase-based enzymes.

Adeogun et al. (2026) studied this question.

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Randomized trial assessed insecticide resistance in Anopheles mosquitoes, indicating significant challenges for malaria control in Nigeria.