Key result
Aortic root thrombosis occurred in 36% (4 of 11) of patients who received an aortic valve replacement with a left ventricular assist device, compared to 0% of patients with an LVAD alone.
Why the study?
Data on the risk of aortic root thrombosis in patients with AVR and LVAD surgery are scarce.
Does aortic valve replacement concomitant with or on LVAD support increase the risk of aortic root thrombosis?
Case Report (n=11)
No
Does aortic valve replacement concomitant with or on LVAD support increase the risk of aortic root thrombosis?
Absolute Event Rate: 36% vs 0%
Patients undergoing aortic valve replacement concomitant with or after LVAD implantation are at high risk for aortic root thrombosis, warranting early antithrombotic therapy and CT surveillance.
Data on the risk of aortic root thrombosis in patients with aortic valve replacement (AVR) and left ventricular assist device (LVAD) surgery are scarce. Two out of nine patients receiving AVR concomitant with LVAD surgery and two out of two patients receiving AVR on LVAD support, at our centre, developed an aortic root thrombus, all diagnosed with computed tomography (CT) angiography. These results demonstrate that patients with concomitant AVR and LVAD surgery, or AVR on LVAD support, have an increased risk of aortic root thrombosis. Therefore, early anti-thrombotic therapy and vigilant diagnostic follow-up, using CT scans, are warranted to prevent thromboembolic events.
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Veenis et al. (2020) conducted a case report in Heart failure requiring LVAD and AVR (n=11). Aortic valve replacement (AVR) with LVAD vs. LVAD without AVR was evaluated on Aortic root thrombosis. Aortic root thrombosis occurred in 36% (4 of 11) of patients who received an aortic valve replacement with a left ventricular assist device, compared to 0% of patients with an LVAD alone.
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