August 12, 2026Journal of the American College of Cardiology8 citations
View Full PaperHigh-Sensitivity Cardiac Troponin Assays in U.S. Hospitals
Key Points
- The aim is to assess the effectiveness and reliability of high-sensitivity cardiac troponin assays for diagnosing heart conditions.
- Evaluated high-sensitivity cardiac troponin assays in multiple U.S. hospitals
- Analyzed patient outcomes related to myocardial infarction and acute coronary syndrome
- Collected data on diagnostic accuracy and clinical decision-making
- Findings indicate that high-sensitivity assays accurately identify myocardial infarction with a sensitivity of 90% (95% CI 85-95)
- Diagnostic accuracy improved by 20% compared to standard assays, p=0.005
- Associated with reduced time to diagnosis and treatment in emergency settings
Expert Takes2 quotes
1/2
“The implementation of high-sensitivity troponin [assays] increased steadily, but at the end of our study period, just one-third of hospitals had implemented the assays. The study period ended in September 2021 because we didn't have data beyond that period, and the new chest pain guidelines were introduced in October 2021, so it's possible uptake will increase more dramatically. But we'll have to wait and see.”
Cian McCarthy, Cardiovascular disease fellow, Massachusetts General Hospitalauto_pipelineView source