Why the study?
Does cardiac resynchronization therapy improve symptoms and survival in patients with left ventricular dysfunction and atrial fibrillation?
Does cardiac resynchronization therapy improve symptoms and survival in patients with left ventricular dysfunction and atrial fibrillation?
This review highlights the pathophysiology and potential benefits of cardiac resynchronization therapy for improving symptoms and survival in patients with concurrent left ventricular dysfunction and atrial fibrillation.
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May support CRT consideration in LV dysfunction with AF; leaves open need for dedicated RCTs to confirm outcomes.
The number of patients with atrial fibrillation and congestive heart failure has steadily increased in the United States. The presence of atrial fibrillation increases morbidity and mortality for patients with left ventricular dysfunction. The emergence of cardiac resynchronization therapy to improve symptoms and survival from congestive heart failure may provide benefits for those with atrial fibrillation; we review the pathophysiology of atrial fibrillation in the presence of left ventricular dysfunction and the promise of cardiac resynchronization therapy to improve symptoms for the for these patients.
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Pelosi et al. (2005) studied this question.
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