Key result
Nascent metabolic syndrome was associated with significantly higher circulating and adipose tissue-released chemerin and lower omentin-1 levels compared to matched controls.
Why the study?
Are circulating and adipose tissue-secreted levels of novel adipokines altered in patients with nascent metabolic syndrome compared to healthy controls?
Population
Subjects with nascent metabolic syndrome and gender- and age-matched controls
Design
Case-control
Authors
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These adipokine shifts support mechanistic inquiry in early metabolic syndrome; should not yet alter clinical practice or risk stratification.
Case-Control
Are circulating and adipose tissue-secreted levels of novel adipokines altered in patients with nascent metabolic syndrome compared to healthy controls?
Nascent metabolic syndrome is associated with abnormal circulating and adipose tissue-secreted levels of chemerin and omentin-1, which may contribute to increased cardiometabolic risk.
Jialal et al. (2013) conducted a case-control in Nascent metabolic syndrome. Nascent metabolic syndrome vs. Gender- and age-matched controls was evaluated on SAT-secreted and plasma levels of chemerin, omentin-1, resistin, and visfatin. Nascent metabolic syndrome was associated with significantly higher circulating and adipose tissue-released chemerin and lower omentin-1 levels compared to matched controls.
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