PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
March 1, 1967Circulation Research36 citationsOpen Access

The Relation of Contractile Enhancement to Action Potential Change in Canine Myocardium

View Full Paper
Ask AI
Bookmark
Share

Population

Canine ventricular tissue

Comparison

Abrupt rate change (cycle-length change) vs Control (stable cycle-length)

Design

Preclinical

Authors

KGKalman GreenspanRERobert E. EdmandsCFCharlés Fisch

Discussion

Loading...

Member takes

Overview

Abrupt changes in heart rate in canine myocardium lead to coupled alterations in action potential configuration and contractile force, suggesting an adaptive mechanism.

Structured PICO

P
Population
Canine ventricular tissue
I
Intervention
Abrupt rate change (cycle-length change)
C
Comparator
Control (stable cycle-length)
O
Outcome
Correlation of action potential alteration with contractile changesurrogate

Abrupt changes in heart rate in canine myocardium lead to coupled alterations in action potential configuration and contractile force, suggesting an adaptive mechanism.

Cite This Study

Greenspan et al. (1967) studied this question.

synapsesocial.com/papers/6a7c7ac1bb130b2209fd6550https://doi.org/10.1161/01.res.20.3.311
View Full Paper
Ask AI
Bookmark
Share