Key result
Prehypertension was associated with significantly higher carotid artery intima media thickness compared to normal blood pressure.
Why the study?
Increased CIMT is linked to CVD risk and documented in hypertension, but early identification of risk factors in prehypertension was needed to help reduce CVD incidence.
Is prehypertension associated with increased carotid artery intima media thickness compared to normal blood pressure?
Observational (n=92)
Is prehypertension associated with increased carotid artery intima media thickness compared to normal blood pressure?
Prehypertension is associated with increased carotid intima media thickness, indicating early structural vascular changes and increased cardiovascular risk.
Answers are grounded in this paper and cite their sources.
Supports early vascular risk assessment in prehypertension; leaves open whether intervention alters progression.
Introduction and Aim: Increased carotid artery intima media thickness (CIMT) has been linked to the development of cardiovascular disease (CVD). CVD is a major cause of mortality and morbidity in India. Increased CIMT has been documented in Hypertension (HT), thus putting them at a higher risk of CVD. Early identification and awareness of risk factors leading to increased morbidity and mortality could help in reducing its incidence. The aim of the study was to measure CIMTin prehypertensive Indian population. Materials and Methods:In this analytical observational study, common carotid artery IMT was measured using B mode ultrasonography in 46 individuals having blood pressure in the prehypertensive range and 46 individuals with normal blood pressure. Cardiovascular risk factors like body mass index(BMI),fasting blood glucose (FBS), and lipid profile, which are known to influence CIMT,were also assessed and compared between the two groups. Results:CIMT was significantly higher in prehypertensives as compared to subjects having normal blood pressure. BMI, FBS, and lipid profile was found to be comparable between the two groups. Conclusions:The presence of increased CIMT in prehypertensives as compared to controls indicates an increased risk of adverse cardiovascular events.
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Basti et al. (2021) conducted an observational in Prehypertension (n=92). Prehypertension vs. Normal blood pressure was evaluated on Carotid artery intima media thickness (CIMT). Prehypertension was associated with significantly higher carotid artery intima media thickness compared to normal blood pressure.
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