Key result
Hypertensive adults had significantly higher CIMT values than non-hypertensive individuals, indicating increased subclinical atherosclerosis risk (p < 0.05).
Why the study?
Carotid intima-media thickness is a surrogate marker for atherosclerosis and cardiovascular events, and the study sought to assess CIMT in hypertensive adults in Port Harcourt to understand vascular wall changes linked to hypertension.
Does hypertension increase carotid intima-media thickness (CIMT) in adults?
Does hypertension increase carotid intima-media thickness (CIMT) in adults?
Hypertensive adults in Nigeria exhibit significantly increased carotid intima-media thickness compared to normotensive controls, supporting the use of sonographic CIMT assessment for subclinical atherosclerosis risk stratification.
Hypertension was associated with higher CIMT in Nigerian adults; confirms prior links yet leaves open whether measurement improves risk stratification.
Carotid Intima-Media Thickness (CIMT) is a reliable surrogate marker for atherosclerosis and can predict future cardiovascular events. The study assessed CIMT in hypertensive adults living in Port Harcourt to understand vascular wall changes linked to hypertension. CIMT was measured in 111 hypertensive and 111 non-hypertensive adults using B-mode ultrasound high-frequency linear probe (7–12 MHz), following Mannheim CIMT Consensus Guidelines. Measurements were taken bilaterally from the common carotid artery (10 mm before bifurcation), focusing on the far wall, and mean CIMT values were calculated. Hypertensive patients showed significantly higher CIMT values (right, left, and mean) compared to non-hypertensive individuals (p < 0.05) Hypertension was more common in older individuals and those with a higher BMI. Age and duration of hypertension had positive correlations with CIMT. BMI showed a weak negative correlation, and only age was statistically significant. Hypertensive adults have increased CIMT, indicating higher risk of subclinical atherosclerosis. The study supports incorporating sonographic CIMT assessment into cardiovascular risk evaluation and preventive healthcare strategies in Nigeria.
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Vahedi et al. (2025) studied this question. Hypertensive adults had significantly higher CIMT values than non-hypertensive individuals, indicating increased subclinical atherosclerosis risk (p < 0.05).
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