Key result
Mean carotid intima media thickness was significantly higher in hypertensive patients compared to healthy controls (0.82 mm vs 0.54 mm, p<0.001) and positively correlated with systolic and diastolic blood pressure.
Why the study?
Hypertension causes structural changes of the intima media of large vessels leading to atheroma formation, which can be estimated via carotid intima media thickness.
Is carotid intima media thickness increased in hypertensive patients compared to healthy controls, and does it correlate with blood pressure?
Case-Control (n=120)
No
Is carotid intima media thickness increased in hypertensive patients compared to healthy controls, and does it correlate with blood pressure?
Absolute Event Rate: 0.82% vs 0.54%
p-value: p=< 0.001
Carotid intima media thickness is significantly increased in hypertensive patients and correlates positively with blood pressure, supporting its use as a noninvasive marker for cardiovascular risk.
CIMT may aid hypertension evaluation; leaves open its incremental prognostic value in prospective studies.
Background: Hypertension will causes structural changes of intima media of large vessels which further causes atheroma formation. Arterial wall thickness can be measured by B-mode ultrasonic measurements of carotid intima media thickness (CIMT) and the extent of carotid atherosclerotic vascular disease may be estimated. The test measures the thickness of the inner two layers of the carotid artery, the intima and the media. Methods: A cross sectional study carried out over a 2 year period. 120 in which 60 are normal healthy individuals and 60 are Hypertensive patients with 3 grades. In all the participants BMI, Blood Pressure and CIMT were measured. Results: In the present study systolic and diastolic blood pressure was significantly increased in hypertension patients compared with Control. The Carotid Intima Media Thickness (CIMT) both Left and Right side were significant higher in Hypertension patients when compared with Control. Blood pressure which includes Systolic and Diastolic blood pressure was positively correlated with cardio vascular risk factor CMIT and it is statistically significant. Conclusion: Present study finding suggested that there is a raised value of CIMT in hypertensive patients. Using CIMT with ultrasonography is a cost effective, noninvasive, easy and reproducible and help as warning signal.
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Raju et al. (2019) conducted a case-control in Hypertension (n=120). Hypertension vs. Normotensive healthy controls was evaluated on Mean Carotid Intima Media Thickness (CIMT) in mm (p=< 0.001). Mean carotid intima media thickness was significantly higher in hypertensive patients compared to healthy controls (0.82 mm vs 0.54 mm, p<0.001) and positively correlated with systolic and diastolic blood pressure.
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