Key result
TAVI significantly improved quality of life (MLHFQ score 28 vs baseline 44, p<0.001) and 6-minute walk test distance (266m vs baseline 204m, p<0.001) at 30 days in severe aortic stenosis.
Why the study?
Does transcatheter aortic valve implantation improve quality of life, exercise capacity, and neurohormonal activation in patients with severe symptomatic aortic stenosis?
Population
44 consecutive patients with symptomatic severe aortic valve stenosis (area<1 cm), age>=75 years with a…
Design
Cohort
Follow-up
30 days
Authors
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Supports short-term QoL and functional gains after TAVI; leaves open durability and effects on hard outcomes.
Cohort (n=44)
Does transcatheter aortic valve implantation improve quality of life, exercise capacity, and neurohormonal activation in patients with severe symptomatic aortic stenosis?
p-value: p=<0.001
TAVI significantly improves quality of life, exercise capacity, and neurohormonal activation at 30 days in patients with severe symptomatic aortic stenosis.
Gotzmann et al. (2009) conducted a cohort in severe and symptomatic aortic valve stenosis (n=44). Transcatheter aortic valve implantation (TAVI) vs. Baseline was evaluated on Quality of life (MLHFQ), 6-minute walk test, and B-type natriuretic peptide (p=<0.001). TAVI significantly improved quality of life (MLHFQ score 28 vs baseline 44, p<0.001) and 6-minute walk test distance (266m vs baseline 204m, p<0.001) at 30 days in severe aortic stenosis.
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