Why the study?
Does milrinone or olprinone improve cardiovascular function in dogs with bupivacaine-induced cardiovascular depression compared to amrinone or saline?
Does milrinone or olprinone improve cardiovascular function in dogs with bupivacaine-induced cardiovascular depression compared to amrinone or saline?
Milrinone and olprinone are as effective as amrinone in reversing bupivacaine-induced cardiovascular depression in an animal model.
No takes yet. Share an insight, caveat, or question.
PDE-3 inhibitors merit evaluation in bupivacaine toxicity models; leaves open human translation and agent selection.
Hirabayashi et al. (2000) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: