Key result
Obesity was not associated with increased recurrent stroke risk (HR 0.95; 95% CI 0.83-1.08) but was associated with a lower risk of major vascular events compared to lean patients.
Why the study?
Does obesity reduce recurrent vascular risk in patients with recent ischemic stroke?
Observational (n=20,246)
Yes
Does obesity reduce recurrent vascular risk in patients with recent ischemic stroke?
Hazard Ratio: 0.95 (95% CI 0.83–1.08)
In patients with recent ischemic stroke, being overweight or obese is associated with a lower risk of subsequent major vascular events compared to being lean, supporting the cardiovascular obesity paradox.
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Supports obesity paradox post-stroke; leaves open whether weight loss modifies recurrent vascular risk in this population.
Ovbiagele et al. (2011) conducted an observational in Recent ischemic stroke (n=20,246). Obesity vs. Lean group was evaluated on Time to first recurrent stroke (HR 0.95, 95% CI 0.83-1.08). Obesity was not associated with increased recurrent stroke risk (HR 0.95; 95% CI 0.83-1.08) but was associated with a lower risk of major vascular events compared to lean patients.
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