Key result
Echocardiographic reference ranges for cardiac chamber size were higher in men than women and varied with age, persisting after normalization for body surface area.
Population
734 healthy volunteers, mean age 45.8 ± 13.3 years, enrolled at 22 collaborating institutions.
Design
Cross-sectional
Authors
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May support sex- and age-specific echocardiographic norms in practice; leaves open prospective outcome validation.
Observational (n=734)
Yes
The NORRE study establishes age- and gender-specific two-dimensional echocardiographic reference ranges for cardiac chamber quantification, emphasizing the importance of body size normalization.
Kou et al. (2014) conducted an observational in Healthy volunteers (n=734). Echocardiographic examination was evaluated on Normal reference ranges for cardiac chambers size. Echocardiographic reference ranges for cardiac chamber size were higher in men than women and varied with age, persisting after normalization for body surface area.
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