Key result
Central serous chorioretinopathy is linked to ~29% higher odds of asymmetric carotid intima-media thickness.
Why the study?
The study was conducted to evaluate common carotid artery intima-media thickness as an indicator of subclinical atherosclerosis in patients with central serous chorioretinopathy.
Is central serous chorioretinopathy associated with differences in common carotid artery intima-media thickness compared to healthy controls?
Case-Control (n=64)
No
Is central serous chorioretinopathy associated with differences in common carotid artery intima-media thickness compared to healthy controls?
Patients with central serous chorioretinopathy exhibit a significantly greater difference in intima-media thickness between the right and left common carotid arteries, suggesting a potential link to subclinical atherosclerosis.
Answers are grounded in this paper and cite their sources.
No CSC management change indicated; leaves open carotid asymmetry as possible atherosclerosis marker pending prospective validation.
Purpose . To evaluate the intima‐media thickness (IMT) of the left and right common carotid arteries (CCA) as an indicator of subclinical atherosclerosis in patients with central serous chorioretinopathy (CSCR). Methods . This was a case‐control study involving patients with CSCR and a matched healthy control group. The mean and difference of the left and right CCA IMT were determined and compared between the two groups using carotid duplex high‐resolution B‐mode ultrasound equipment. Results . The study enrolled 32 CSCR patients (68.8% female, mean age 38.22 ± 5.42 years) and 32 controls (65.6% female, mean age 39.56 ± 5.33 years). The difference in common carotid IMT between the right and left sides was significantly greater in the CSCR group than in the control group ( p < 0.001). Additionally, according to logistic regression analysis, patients with CSCR had a greater chance of having differences in IMT between the two sides when compared to the control group (OR: 1.29, 95% CI: 1.09–1.52). Conclusion . Our findings indicated that in the CSCR group, the difference between the right and left sides of CCA IMT was significantly greater than in the control group.
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Nasrollahi et al. (2021) conducted a case-control in Central serous chorioretinopathy (CSCR) (n=64). Central serous chorioretinopathy (CSCR) vs. Healthy matched controls was evaluated on Difference between right and left common carotid artery intima-media thickness (CCA IMT) (OR 1.29, 95% CI 1.09-1.52, p=<0.001). Central serous chorioretinopathy was associated with a greater side-to-side difference in common carotid artery intima-media thickness compared to controls.
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