January 1, 1993Diabetes
Attenuated Fibrinolysis and Accelerated Atherogenesis in Type II Diabetic Patients
Population
Type II diabetic patients
Design
Review
Authors
Discussion
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Member takes
Implication
May link hyperinsulinemia to thrombosis in diabetes; hypothesis-generating for targeted therapies.
Structured PICO
P
Population
Type II diabetic patients
Hyperinsulinemia in type II diabetes may contribute to macrovascular disease by increasing PAI-1 levels and impairing endogenous fibrinolysis, thereby promoting atherogenesis.
Cite This Study
Schneider et al. (1993) studied this question.