Key result
Anti-hypertensive drugs induced various degrees of hypertrophic regression, with indapamide showing stronger effects than enalapril, and losartan producing better results than atenolol.
Why the study?
Do different anti-hypertensive drugs have varying effects on the regression of left ventricular hypertrophy?
Population
Subjects (including animal models such as LVH rats) with left ventricular hypertrophy
Comparison
Anti-hypertensive drugs vs Other anti-hypertensive drugs
Design
Meta-analysis
Authors
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Supports preferential use of indapamide or losartan for LVH regression; extends comparative effectiveness data from prior trials.
Meta-Analysis
Do different anti-hypertensive drugs have varying effects on the regression of left ventricular hypertrophy?
Different classes of anti-hypertensive drugs have varying efficacies in inducing the regression of left ventricular hypertrophy, with indapamide and losartan showing superior effects compared to enalapril and atenolol, respectively.
Filho et al. (2010) conducted a meta-analysis in Left ventricular hypertrophy. Anti-hypertensive drugs was evaluated on Ventricular hypertrophy regression. Anti-hypertensive drugs induced various degrees of hypertrophic regression, with indapamide showing stronger effects than enalapril, and losartan producing better results than atenolol.
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