Key result
The Mosaic porcine bioprosthesis in the mitral position demonstrated satisfactory long-term durability, with a 12-year overall survival rate of 54.1% and a 12-year freedom from structural valve deterioration of 77.9%.
Cohort (n=390)
Yes
The Mosaic porcine bioprosthesis in the mitral position provides satisfactory long-term durability and survival up to 12 years, suggesting it is a reasonable alternative to mechanical valves even in patients under 65 years old.
Background:This study retrospectively evaluated the long-term patient outcomes and durability of the Mosaic mitral porcine bioprosthesis in the Japan Mosaic valve long-term multicenter study.
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A 2021 study conducted a cohort in Mitral valve disease requiring replacement (n=390). Mosaic mitral porcine bioprosthesis was evaluated on 12-year overall survival. The Mosaic porcine bioprosthesis in the mitral position demonstrated satisfactory long-term durability, with a 12-year overall survival rate of 54.1% and a 12-year freedom from structural valve deterioration of 77.9%.
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