Why the study?
How does hemorrhagic shock affect left ventricular dimensions and volume in a canine model?
Population
15 splenectomized dogs
Comparison
Hemorrhagic shock vs Baseline (pre-hemorrhage)
Design
Preclinical
Follow-up
3 hours
Authors
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Highlights preload dependence of LV function in hemorrhagic shock; leaves open translation to clinical resuscitation.
How does hemorrhagic shock affect left ventricular dimensions and volume in a canine model?
Hemorrhagic shock causes a pronounced reduction in the minor axes of the left ventricle, leading to reduced ventricular volume and function.
Horton et al. (1992) studied this question.
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