Why the study?
To compare cardiovascular changes and side effects of administering propofol alone versus propofol with rocuronium bromide during electroconvulsive therapy.
Does adding rocuronium to propofol induction improve cardiovascular stability and reduce side effects in patients undergoing electroconvulsive therapy?
Does adding rocuronium to propofol induction improve cardiovascular stability and reduce side effects in patients undergoing electroconvulsive therapy?
Adding rocuronium to propofol for ECT induction reduces postoperative myalgia without significantly altering cardiovascular parameters, though it slightly prolongs recovery time.
Answers are grounded in this paper and cite their sources.
Propofol-rocuronium during ECT shows no clear hemodynamic advantage; leaves open optimal regimen pending higher-level evidence.
Aim: In this study, we aimed to compare groups in terms of cardiovascular changes and side effects by administering propofol to patients in the control group and propofol and rocuronium bromide to patients in the study group during electroconvulsive therapy. Material and Methods: Eighty-four patients with ASA I-II schizophrenia, major depression and bipolar disease were included in the study. Heart rate, MAP (mmHg) and ECG of the patients were recorded both before induction and at the end of convulsion. Patients in the R group (n = 42) were administered with 2% lidocaine IV 0,5 mg / kg, propofol IV 1-2 mg / kg and rocuronium IV 0,2 mg / kg for induction. Patients in the P group (n = 42) were given 2% lidocaine IV 0,5 mg / kg and propofol IV 1-2 mg / kg only for induction. Results: Pd values before induction were statistically lower than Pd values after ECT in both P and R groups. In both patients in the P group and the R group, the post-ECT values for HR were statistically higher than the pre-induction values. Pre-induction MAP values were statistically lower than post-ECT MAP values in both P and R groups. Discussion: In ECT, when we compare the application of propofol and rocuronium with the application of propofol without muscle relaxants, propofol as an anesthetic agent provided an adequate and safe anesthesia with rapid recovery and a minimal side effect profile except for postoperative temporary myalgia in these patients.
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A 2022 study studied this question.
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