Why the study?
Does fixed-dose combination antihypertensive therapy improve adherence and blood pressure control in patients with hypertension?
Does fixed-dose combination antihypertensive therapy improve adherence and blood pressure control in patients with hypertension?
Fixed-dose combination antihypertensive therapy simplifies treatment, improves patient adherence, and enhances blood pressure control and target organ protection in hypertensive patients.
May support fixed-dose combinations for adherence; leaves open randomized confirmation of BP control.
Control over blood pressure is an existing problem in cardiology and does not exceed 30 % for Europeans, despite prevalence and availability of effective antihypertensive drugs. Low adherence to treatment is one of the reasons of low control of blood pressure. Implementation of the combined antihypertensive drugs with the high fixed doses allows to simplify therapy in subjects receiving combination therapy and to increase the adherence in high risk patients receiving drugs separately.
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И. И. Чукаева (2012) studied this question.
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