Key result
Dual and triple combination therapy for hypertension provides good clinical outcomes, compliance, and a low profile of side effects, with future trends pointing toward combinations including statins.
Why the study?
Does fixed combination antihypertensive therapy improve clinical outcomes, tolerability, and patient compliance compared to monotherapy in hypertensive patients?
Does fixed combination antihypertensive therapy improve clinical outcomes, tolerability, and patient compliance compared to monotherapy in hypertensive patients?
Fixed-dose combination antihypertensive therapy is recommended to improve patient adherence, enhance blood pressure control, and reduce long-term cardiovascular adverse events.
Authors
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May support guideline-recommended combination therapy in high-risk hypertension; leaves open optimal regimens for subgroups.
Łopatowska et al. (2017) conducted a review in Hypertension. Fixed combinations of antihypertensive drugs was evaluated. Dual and triple combination therapy for hypertension provides good clinical outcomes, compliance, and a low profile of side effects, with future trends pointing toward combinations including statins.
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