Why the study?
Does fetal cardiac surgery prevent progression to single ventricle circulation in fetuses with critical aortic or pulmonary stenosis?
Does fetal cardiac surgery prevent progression to single ventricle circulation in fetuses with critical aortic or pulmonary stenosis?
Fetal cardiac interventions for critical aortic or pulmonary stenosis can reverse heart failure and achieve postnatal biventricular circulation in approximately two-thirds of successful cases.
May support fetal intervention to avert single-ventricle circulation in select cases; leaves open the need for prospective trials before practice change.
Intrauterine dilation of critical fetal aortic stenosis (AS) and pulmonary stenosis or atresia has the potential to change the natural course of these congenital heart defects preventing progression to a single ventricle circulation. This article reviews the world experience in fetal cardiac interventions. In carefully selected cases, fetal cardiac surgery can reverse end-stage heart failure and can provide biventricular outcome postnatally in about two thirds of the cases with successful interventions.
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Arzt et al. (2011) studied this question.
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