Why the study?
Radiation-associated angiosarcoma of the breast carries a very poor prognosis when locally recurrent or unresectable, and the role of adjuvant and systemic therapies remains controversial.
Does combined wIRA-hyperthermia and re-irradiation improve local control in patients with radiation-associated angiosarcoma of the breast?
Population
10 consecutive patients with radiation-associated angiosarcoma of the breast
Comparison
Thermography-controlled wIRA superficial hyperthermia immediately followed by re-irradiation
Design
Retrospective study
Authors
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Retrospective RAASB series underscores poor outcomes in recurrent disease; leaves open optimal adjuvant strategies for prospective evaluation.
Does combined wIRA-hyperthermia and re-irradiation improve local control in patients with radiation-associated angiosarcoma of the breast?
Combined hyperthermia and re-irradiation may offer a viable treatment option for adjuvant or definitive management of radiation-associated angiosarcoma of the breast.
Notter et al. (2021) studied this question.
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