August 1, 1999European Journal of Heart Failure
Tailored Therapy to Hemodynamic Goals for Advanced Heart Failure
Population
Approximately 1,500 patients with advanced heart failure managed at UCLA and Brigham and Women's Hospital.
Design
Review
Authors
Discussion
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Member takes
Implication
May support hemodynamic tailoring in advanced HF; leaves open effects on clinical outcomes.
Structured PICO
P
Population
Approximately 1,500 patients with advanced heart failure managed at UCLA and Brigham and Women's Hospital.
I
Intervention
Tailored therapy to hemodynamic goals (reducing filling pressures to near-normal levels using vasodilators and diuretics, often guided by invasive monitoring).
Tailoring medical therapy to specific hemodynamic goals in advanced heart failure can effectively reduce filling pressures, improve cardiac index, and ameliorate congestive symptoms.
Cite This Study
Lynne W. Stevenson (1999) studied this question.