July 8, 2011EP Europace
Induction and aggravation of atrioventricular valve regurgitation in the course of chronic right ventricular apical pacing
Why the study?
Does right ventricular apical pacing aggravate atrioventricular valve regurgitation in patients with high-degree AV block?
Population
125 patients requiring dual-chamber pacemakers due to high-degree AV block with normal left ventricular…
Comparison
Right ventricular apical pacing via permanent… vs Baseline (pre-implantation status)
Design
Cohort
Follow-up
mean 4.08 ± 0.8 years
Authors
Discussion
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Member takes
Implication
May warrant echocardiographic surveillance after RV apical pacing; leaves open whether alternative sites mitigate regurgitation risk.
Structured PICO
Does right ventricular apical pacing aggravate atrioventricular valve regurgitation in patients with high-degree AV block?
P
Population
125 patients requiring dual-chamber pacemakers due to high-degree AV block with normal left ventricular function before implantation, mean age 66.57, 61 male.
I
Intervention
Right ventricular (RV) apical pacing via permanent dual-chamber pacemaker
C
Comparator
Baseline (pre-implantation status)
O
Outcome
Severity of tricuspid regurgitation (TR) and mitral regurgitation (MR) assessed by echocardiographysurrogate
Chronic right ventricular apical pacing is associated with a significant increase in the prevalence and severity of tricuspid and mitral regurgitation, despite preserved left ventricular function.
Cite This Study
Alizadeh et al. (2011) studied this question.