Why the study?
The study aimed to evaluate the effectiveness of prognostic markers in predicting 90-day mortality in patients hospitalized with acute decompensated heart failure.
Elevated BUN, lactate, and age, along with decreased albumin, are strong independent predictors of 90-day mortality in patients with acute decompensated heart failure, which can aid in early risk stratification.
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May identify ADHF prognostic markers; leaves open need for prospective validation before clinical use.
Purpose: This study aims to evaluate the effectiveness of prognostic markers in predicting 90-day mortality in patients admitted to the hospital with a diagnosis of acute decompensated heart failure (ADHF). Materials and Methods: This retrospective study analyzed data from 559 ADHF patients admitted between 01.05.2023 and 01.09.2024. Age, sex, laboratory parameters, and 90-day mortality data were collected, and independent variables affecting mortality were evaluated via logistic regression and receiver operating characteristic (ROC) analysis. Results: Age, blood urea nitrogen, albumin, and lactate levels were identified as independent predictors of 90-day mortality. The blood urea nitrogen level demonstrated the highest area under the curve (AUC = 0.673) for a cutoff value of 30.9 mg/dL. A significant increase in mortality risk was observed for patients with lactate levels >1.45 mmol/L. Conclusion: Age, blood urea nitrogen, albumin, and lactate levels are strong prognostic markers for 90-day mortality in patients with ADHF. These findings may contribute to early risk stratification and the development of personalized treatment strategies.
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Köksal et al. (2025) studied this question.
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