Why the study?
Are blood pressure and heart rate variability altered in patients with Alzheimer's disease compared to controls and those with mild cognitive impairment?
Population
103 subjects including patients with Alzheimer's disease, mild cognitive impairment, subjective memory…
Design
Case-control
Follow-up
24 hours
Authors
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May indicate autonomic dysregulation in early AD; hypothesis-generating for longitudinal studies before informing practice.
Are blood pressure and heart rate variability altered in patients with Alzheimer's disease compared to controls and those with mild cognitive impairment?
Mild cholinesterase-naive AD patients exhibit disturbed diurnal sympathetic and parasympathetic cardiac variability and blunted nocturnal BP dipping.
Kim et al. (2015) studied this question.
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