Population
Anesthetized cats
Design
Preclinical
Follow-up
120 minutes of occlusion followed by reperfusion
Authors
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Caution against clinical extrapolation from feline ischemia; extends understanding of time-dependent NE kinetics in reperfusion.
In an in vivo cat model of myocardial ischemia and reperfusion, intraneuronal DHPG production and NE kinetics vary significantly with the duration of occlusion and reperfusion.
T. Akiyama (2001) studied this question.
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