Population
Bovine Arp2/3 complex
Design
Preclinical
Authors
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Enables mechanistic modeling of Arp2/3 activation; leaves open translation to human cardiovascular actin biology.
Provides the crystal structure of the Arp2/3 complex, offering insights into how WASp/Scar proteins activate it for actin filament nucleation.
Robinson et al. (2001) studied this question.
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