Why the study?
Are eNOS gene polymorphisms 894G>T and 4a/4b associated with the presence of coronary artery disease in a Tunisian population?
Population
700 individuals from Tunisia, comprising 332 patients with coronary artery disease (CAD) and 368 controls.
Comparison
Presence of eNOS gene polymorphisms 894G>T and… vs Absence of these polymorphisms (controls)
Design
Case-control
Authors
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May inform CAD risk stratification in Tunisians; leaves open replication in prospective cohorts before clinical use.
Are eNOS gene polymorphisms 894G>T and 4a/4b associated with the presence of coronary artery disease in a Tunisian population?
The G894T (rs1799983) polymorphism of the eNOS gene is significantly associated with genetic susceptibility to coronary artery disease in the Tunisian population.
Ali et al. (2015) studied this question.
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