Why the study?
Does long-acting propranolol 160 mg daily improve blood pressure reduction compared to conventional propranolol in moderately hypertensive subjects?
Population
11 moderately hypertensive subjects previously shown to respond to propranolol
Comparison
Long-acting formulation of propranolol 160 mg… vs Conventional propranolol 80 mg twice daily or…
Design
Other
Follow-up
1 month
Authors
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LA propranolol may enhance 24-h systolic BP control; hypothesis-generating and should not yet change practice.
Does long-acting propranolol 160 mg daily improve blood pressure reduction compared to conventional propranolol in moderately hypertensive subjects?
Long-acting propranolol 160 mg daily provides superior 24-hour systolic blood pressure reduction compared to conventional propranolol despite lower overall plasma concentrations.
Serlin et al. (1983) studied this question.