Why the study?
Does head-up tilt and altered PCO2 affect cerebrovascular autoregulation as measured by the transfer function relating BP to cerebrovascular resistance in human subjects?
Population
9 subjects
Comparison
Head-up tilt and altered arterial PCO2 vs Supine position with normal end-tidal PCO2
Design
Other
Authors
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May influence autoregulation testing protocols; hypothesis-generating and should not yet alter clinical practice.
Does head-up tilt and altered PCO2 affect cerebrovascular autoregulation as measured by the transfer function relating BP to cerebrovascular resistance in human subjects?
Transfer function analysis of blood pressure to cerebrovascular resistance provides direct evidence of altered cerebrovascular autoregulation under head-up tilt and higher levels of PCO2.
Edwards et al. (2002) studied this question.
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