Why the study?
Does heparin interfere with albumin determination by dye-binding methods?
Does heparin interfere with albumin determination by dye-binding methods?
High concentrations of heparin interfere with albumin determination using bromcresol green, an effect that can be mitigated by using bromcresol purple or adding hexadimethrine bromide.
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May prompt labs to prefer bromcresol purple or additives for heparinized samples; leaves open clinical impact and needs human validation.
Bonvicini et al. (1979) studied this question.
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