Why the study?
Does percutaneous pulmonary valvuloplasty improve transvalvular gradient and right heart function in patients with pulmonary valve stenosis?
Does percutaneous pulmonary valvuloplasty improve transvalvular gradient and right heart function in patients with pulmonary valve stenosis?
Percutaneous pulmonary valvuloplasty is an effective and safe treatment for pulmonary valve stenosis, significantly reducing transvalvular gradients with good mid-term outcomes.
Case report suggests feasibility in pulmonary stenosis; leaves open randomized confirmation of durability and right heart effects.
BACKGROUND: Percutaneous pulmonary valvuloplasty is well established treatment of choice in pulmonary valve stenosis. AIM: The aim of our study was to present our experience with the interventional technique, its immediate and mid-term effectiveness as well as its complication rate. MATERIAL AND METHODS: The study included 43 patients, where 33 (74%) of them were children between the age of 1 month and 15 years. RESULTS: The procedure was successful in 38 patients or 90%. Mean peak to peak transvalvular gradient was reduced from 91.2 mmHg (55-150 mmHg) to 39.1 mmHg (20-80 mmHg). Follow- up of patients was between 2 and 13 years and included echocardiographic evaluation of pulmonary valve gradient, right heart dimensions and function as well as assessment of pulmonary regurgitation. We experienced one major complication pericardial effusion in a 5 months old child that required pericardiocenthesis. Six patients (13.9%) required a second intervention. During the follow up period there was significant improvement of right heart function and echocardiography parameters. Mild pulmonary regurgitation was noted in 24 (55%) patients, and four (9%) patients developed moderate regurgitation, without affecting the function of the right ventricle. CONCLUSIONS: Percutaneous pulmonary valvuloplasty is an effective procedure in treatment of pulmonary stenosis with good short and mid-term results.
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Idrizi et al. (2015) studied this question.
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