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January 21, 2024ESC Heart FailureOpen Access

The group with the highest TyG index had significantly higher post-PCI MACE rates than the lowest index group, with HR 2.04 (95% CI 1.65–2.52; I2 = 77%).

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Why the study?

PCI addresses myocardial ischaemia, but a significant subset of patients encounter major adverse cardiovascular events post-treatment.

Does an elevated triglyceride-glucose (TyG) index predict major adverse cardiovascular events in patients post-percutaneous coronary intervention?

Population

Patients post-PCI in China

Comparison

Highest vs lowest TyG index group or per unit increase in TyG index

Design

Meta-analysis

Authors

CSChangXin SunLHLanQing HuXLXiaoya Li

Discussion

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Member takes

Overview

May inform post-PCI risk stratification; leaves open whether TyG-targeted interventions reduce events.

Structured PICO

Does an elevated triglyceride-glucose (TyG) index predict major adverse cardiovascular events in patients post-percutaneous coronary intervention?

P
Population
Patients post-percutaneous coronary intervention (PCI) in China
I
Intervention
Highest triglyceride-glucose (TyG) index group or per unit increase in TyG index
C
Comparator
Lowest triglyceride-glucose (TyG) index group
O
Outcome
Major adverse cardiovascular events (MACE)composite

An elevated triglyceride-glucose index is significantly associated with an increased risk of MACE and other adverse cardiovascular outcomes in patients following percutaneous coronary intervention.

Cite This Study

Sun et al. (2024) studied this question.

synapsesocial.com/papers/6a7d0b884bbb2340c9d59d6dhttps://doi.org/10.1002/ehf2.14679
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The impact of triglyceride-glucose index on the prognosis of post-PCI patients–a meta-analysis2024 · 8 citations
  2. 2Triglyceride glucose index in patients with acute coronary syndrome undergoing percutaneous coronary intervention predicts cardiovascular events: a cohort study2025 · 5 citations
  3. 3Triglyceride-glucose index as a predictor of adverse cardiovascular outcomes in a contemporary, diverse US population undergoing percutaneous coronary intervention2026
  4. 4The Prognostic Value of the Triglyceride-Glucose Index in Forecasting Ten-Year Major Adverse Cardiovascular Events in Non-Diabetic Patients with Acute Myocardial Infarction Undergoing Percutaneous Coronary Intervention2024 · 4 citations
  5. 5Prognostic significance of the triglyceride-glucose index for patients with ischemic heart failure after percutaneous coronary intervention2023 · 33 citations