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June 12, 2018Journal of Cardiovascular MedicineOpen Access

Long-term dual antiplatelet therapy: pharmacological and clinical implications

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Why the study?

Does long-term dual antiplatelet therapy improve clinical outcomes in patients with acute coronary syndrome?

Population

Patients experiencing an acute coronary syndrome or previous myocardial infarction

Design

Review

Authors

CMCarlo Di MarioAMAlessandro MugelliPFPasquale Perrone Filardi

Discussion

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Member takes

Overview

Supports individualized DAPT decisions in high-risk ACS; leaves open confirmation by randomized trials.

Structured PICO

Does long-term dual antiplatelet therapy improve clinical outcomes in patients with acute coronary syndrome?

P
Population
Patients experiencing an acute coronary syndrome or previous myocardial infarction
I
Intervention
Long-term dual antiplatelet therapy (over 12 months)

Long-term DAPT (>12 months) may improve outcomes in high-risk ACS patients, highlighting the need for personalized therapy to balance ischemic and bleeding risks.

Cite This Study

Mario et al. (2018) studied this question.

synapsesocial.com/papers/6a7d0bbfec6dad7f5aaa073fhttps://doi.org/10.2459/jcm.0000000000000677
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