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April 8, 2008Hypertension

Resistant Hypertension: Diagnosis, Evaluation, and Treatment

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Population

Patients with resistant hypertension

Design

Review

Authors

DCDavid A. CalhounGeneral CardiologyDJDaniel JonesUniversity of Nevada, RenoSTStephen C. TextorVascular Medicine

Discussion

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Overview

Supports secondary cause screening and multidrug regimens in resistant hypertension; leaves open optimal combinations for prospective trials.

Structured PICO

P
Population
Patients with resistant hypertension

This review highlights the multifactorial etiology of resistant hypertension and the need for comprehensive evaluation, lifestyle modification, and multidrug regimens.

Limitations

  • high cardiovascular risk of patients precludes safe withdrawal of medications
  • presence of multiple disease processes and associated medical therapies confound interpretation
  • difficulty in enrolling large numbers of study participants

Cite This Study

Calhoun et al. (2008) studied this question.

synapsesocial.com/papers/6a7d0f4b58b935a3e446cab4https://doi.org/10.1161/hypertensionaha.108.189141

Topics

Hypertension management
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Also Consider

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  1. 1Twenty-four hour ambulatory blood pressure monitoring pattern of resistant hypertension2003 · 136 citations
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  3. 3Sodium restriction in hypertensive patients treated with a converting enzyme inhibitor and a thiazide.1991 · 49 citations
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  5. 5Effects of Time of Day of Treatment on Ambulatory Blood Pressure Pattern of Patients With Resistant Hypertension2005 · 124 citations