Why the study?
Does trimetazidine improve resting energy expenditure and left ventricular function in patients with chronic systolic heart failure?
Population
44 patients with chronic systolic heart failure receiving full medical treatment
Comparison
Trimetazidine added to conventional treatment… vs Conventional therapy alone
Design
RCT, randomised, Single blind
Follow-up
3 months
Authors
Loading...
Trimetazidine addition improves EF and REE in systolic HF; extends metabolic modulation evidence for LV function.
Does trimetazidine improve resting energy expenditure and left ventricular function in patients with chronic systolic heart failure?
In patients with systolic heart failure, the addition of trimetazidine to conventional therapy for 3 months improves left ventricular ejection fraction, functional class, and reduces resting energy expenditure.
Fragasso et al. (2011) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: