September 1, 1985AJP Cell Physiology

Myosin phosphorylation, force, and maximal shortening velocity in neurally stimulated tracheal smooth muscle

View Full Paper

Ask AI

Bookmark

Population

Bovine tracheal smooth muscle strips

Comparison

Field stimulation of intrinsic nerves vs Addition of carbamylcholine to the bathing medium

Design

Preclinical

Authors

KKKristine E. KammThe University of Texas Southwestern Medical Center JSJames T. StullHeart Failure / Cardiomyopathy

Discussion

Member takes

Implication

Supports myosin phosphorylation regulating cross-bridge cycling in smooth muscle; leaves open human translation.

Structured PICO

Population

Bovine tracheal smooth muscle strips

Intervention

Field stimulation of intrinsic nerves

Comparator

Addition of carbamylcholine to the bathing medium

Outcome

Myosin light chain phosphorylation, maximal shortening velocity (Vo), and isometric forcesurrogate

The temporal correlation between light chain phosphorylation and maximal shortening velocity supports the hypothesis that myosin phosphorylation regulates cross-bridge cycling rates in smooth muscle.

Cite This Study

Kamm et al. (1985) studied this question.

synapsesocial.com/papers/6a7d16e92935e92dbc775554 https://doi.org/10.1152/ajpcell.1985.249.3.c238

View Full Paper

Ask AI

Bookmark

Myosin phosphorylation, force, and maximal shortening velocity in neurally stimulated tracheal smooth muscle

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Myosin phosphorylation, force, and maximal shortening velocity in neurally stimulated tracheal smooth muscle

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider