Why the study?
Does early administration of abciximab bolus in the emergency department improve angiographic outcomes in AMI patients planned for primary PCI?
Population
80 acute myocardial infarction (AMI) patients with planned percutaneous coronary intervention (PCI)
Comparison
0.25 mg/kg abciximab bolus administered 'early'… vs 0.25 mg/kg abciximab bolus administered 'late'…
Design
RCT, randomized, double-blind fashion
Follow-up
30 days
Authors
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Supports early abciximab in the ED before primary PCI; extends evidence for upstream GP IIb/IIIa use in AMI.
Does early administration of abciximab bolus in the emergency department improve angiographic outcomes in AMI patients planned for primary PCI?
Early administration of abciximab in the emergency department prior to primary PCI significantly improves post-PCI coronary flow and myocardial reperfusion compared to late administration in the cath lab.
Gabriel et al. (2006) studied this question.
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