Why the study?
Does coronary oxygen persufflation improve functional and metabolic recovery in mature pig hearts after 14-hour hypothermic preservation compared to simple storage solutions?
Population
Mature pig hearts undergoing orthotopic transplantation
Comparison
14-hour hypothermic preservation using coronary… vs 14-hour simple hypothermic storage in University…
Design
Preclinical
Follow-up
2 hours
Authors
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May support COP for extended porcine preservation; hypothesis-generating and requires human translation before any clinical consideration.
Does coronary oxygen persufflation improve functional and metabolic recovery in mature pig hearts after 14-hour hypothermic preservation compared to simple storage solutions?
Coronary oxygen persufflation significantly improves the functional and metabolic recovery of pig hearts after prolonged 14-hour hypothermic storage compared to standard preservation solutions.
Fischer et al. (1998) studied this question.
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