Why the study?
Does the physiological stimulus for exercise-induced secretion of BNP and ANP differ between patients with essential hypertension and normal subjects?
Population
33 subjects, comprising 19 patients with essential hypertension and 14 normal control subjects.
Comparison
Exercise with a bicycle ergometer. vs Normal control subjects and baseline resting…
Design
Cross-sectional
Authors
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Altered correlations in hypertension suggest modified regulation; this Level 4 observation leaves open causal mechanisms and clinical relevance.
Does the physiological stimulus for exercise-induced secretion of BNP and ANP differ between patients with essential hypertension and normal subjects?
The physiological mediators for exercise-induced BNP and ANP release are altered in essential hypertension, shifting from sympathetic stimuli in normal subjects to heart rate in hypertensives.
Tanaka et al. (1995) studied this question.
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