Why the study?
Does Angiotensin II infusion enhance thrombosis development in renovascular hypertensive rats?
Population
Renovascular hypertensive rats with venous thrombosis induced by ligation of vena cava
Design
Preclinical
Authors
Loading...
Hypothesis-generating for AT1-mediated venous thrombosis in renovascular hypertension; should not yet change clinical practice.
Does Angiotensin II infusion enhance thrombosis development in renovascular hypertensive rats?
In vivo evidence demonstrates that Angiotensin II promotes venous thrombosis development via the AT1 receptor, partially mediated by Angiotensin IV, increased leukocyte adhesion, and elevated PAI-1.
Mogielnicki et al. (2005) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: