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January 1, 2007Respiration

Systolic PAP >35 mm Hg was found in 56% (14/25) of patients receiving hemodialysis and in 39.1% (9/23) of predialysis patients, with elevated PAP associated with increased parathyroid hormone, cardiac output, and CRF duration (p < 0.05).

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Population

48 patients with chronic renal failure without comorbid conditions causing pulmonary hypertension, including…

Design

Cohort

Follow-up

7.5 +/- 1.01 months

Authors

SKSeyhun KürşatCECumhur Gökhan EkmekçiPÇPınar Çelik

Discussion

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Overview

Elevated PAP prevalence in CRF warrants attention; hypothesis-generating for PTH, output, and duration as contributors.

Structured PICO

P
Population
48 patients with chronic renal failure (CRF) without comorbid conditions causing pulmonary hypertension (20 males, 28 females), including 23 predialysis patients and 25 receiving hemodialysis via arteriovenous fistula (AVF).
O
Outcome
Incidence of unexplained pulmonary hypertension (systolic PAP >35 mm Hg) and evaluation of possible etiologic factorssurrogate

A high incidence of unexplained pulmonary hypertension exists in patients with chronic renal failure, potentially driven by factors such as AVF flow, cardiac output, and parathyroid hormone levels.

Cite This Study

Kürşat et al. (2007) studied this question.

synapsesocial.com/papers/6a7d24fc3575152c8237d27ahttps://doi.org/10.1159/000102953
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1PH Grand Rounds: A Case of Pulmonary Hypertension Associated With High Cardiac Output State from Arteriovenous Fistula–Or Is It?2019
  2. 2Pulmonary hypertension in patients on chronic hemodialysis and with heart failure2015 · 9 citations
  3. 3Prevalence of pulmonary hypertension in patients with chronic kidney disease on and without dialysis2013 · 19 citations
  4. 4Prevalence and Predictors of Pulmonary Hypertension in End-Stage Renal Disease: a Single-Center Cross-Sectional Study2026
  5. 5#52 Pulmonary hypertension in hemodialysis patients: prevalence and risk factors: a single center study2024