Why the study?
Does irbesartan reduce blood pressure and demonstrate appropriate pharmacokinetics in hypertensive children and adolescents?
Does irbesartan reduce blood pressure and demonstrate appropriate pharmacokinetics in hypertensive children and adolescents?
Irbesartan at 2 mg/kg once daily shows similar pharmacokinetics to adults and effectively reduces blood pressure in hypertensive children and adolescents.
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May support irbesartan in hypertensive children; leaves open confirmation in larger randomized trials.
Şakarcan et al. (2001) studied this question.
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