Population
Rabbit cardiac Purkinje fibres (short preparations)
Comparison
Acetylcholine (ACh) vs Control conditions
Design
Preclinical
Authors
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ACh effects on rabbit Purkinje currents should not change practice; extends mechanistic insights but leaves open human translation.
Acetylcholine modulates cardiac electrophysiology in rabbit Purkinje fibers by altering specific potassium currents and counteracting beta-adrenergic stimulation of slow inward currents.
Carmeliet et al. (1986) studied this question.
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