Why the study?
While direct oral anticoagulants like dabigatran cause fewer bleeding complications than warfarin, severe intracranial hemorrhages remain lethal.
Idarucizumab administration prior to emergency neurosurgery in a patient on dabigatran with intracranial hemorrhage allowed for minimized intraoperative bleeding and safe perioperative management.
Idarucizumab enabled hemostatic control during emergency neurosurgery for dabigatran-related intracranial bleed; leaves open broader outcome benefits in prospective studies.
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Sato et al. (2019) studied this question.
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