Why the study?
Side effects of selective serotonin reuptake inhibitors are usually underreported in clinical trials, warranting systematic evaluation using structured instruments in a naturalistic setting.
What is the side effect profile of commonly used SSRIs in a naturalistic treatment setting?
Population
100 patients on SSRI monotherapy
Comparison
Sertraline vs escitalopram vs fluoxetine
Design
Naturalistic observational study using a self-rating instrument
Authors
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Highlights underreported SSRI side effects in practice; leaves open agent-specific profiles for randomized confirmation.
What is the side effect profile of commonly used SSRIs in a naturalistic treatment setting?
SSRIs are associated with high rates of subjective side effects in naturalistic settings, with specific profiles varying by drug, such as more cognitive and dizziness symptoms with escitalopram and decreased appetite with sertraline.
Anagha et al. (2021) studied this question.
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