Population
Stably transfected McA-RH7777 rat hepatoma cells and Chinese hamster ovary cells
Design
Preclinical
Authors
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ApoA-V may limit hepatic VLDL secretion in models; hypothesis-generating for human dyslipidemia, should not change practice.
ApoA-V inefficiently traffics within the secretory pathway, and its synthesis can modulate VLDL triglyceride mobilization and secretion.
Blade et al. (2010) studied this question.
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